Advances in the diagnosis and neurorehabilitation of spatial neglect and distractor inhibition impairments using XR

(2026)

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Abstract
(en) Stroke frequently results in attentional impairments that limit functional recovery. Although virtual reality and serious games have shown potential for cognitive assessment and rehabilitation, current approaches remain limited in their ability to characterize underlying attentional processes and to individualize rehabilitation. This thesis presents the development of the REAsmash framework to improve the assessment and rehabilitation of post-stroke spatial and non-spatial attentional impairments using extended reality technologies. Across four studies, REAsmash evolved from a serious game assessing spatial attention and distractor inhibition to an integrated framework combining immersive virtual reality, eye-tracking, upper-limb kinematics, and adaptive rehabilitation through a theory-driven dynamic difficulty adjustment algorithm. Overall, this work supports the feasibility of using XR technologies to provide more sensitive assessment and individualized cognitive rehabilitation following stroke.
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Sorrentino, G. (2026). Advances in the diagnosis and neurorehabilitation of spatial neglect and distractor inhibition impairments using XR. https://hdl.handle.net/2078.5/280284