Population pharmacokinetics and dosing simulations of total and unbound temocillin in the plasma and CSF of neurocritically ill patients with external ventricular drain-related cerebral ventriculitis

Ngougni Pokem, P., Liu, X., Parker, S. L., Verroken, A., Collienne, C., Finet, P., Wijnant, G.-J., Laterre, P.-F., Roberts, J. A., Van Bambeke, F., & Wittebole, X. (2024). Population pharmacokinetics and dosing simulations of total and unbound temocillin in the plasma and CSF of neurocritically ill patients with external ventricular drain-related cerebral ventriculitis. Journal of Antimicrobial Chemotherapy, 79(2), 429-442. https://doi.org/10.1093/jac/dkad398 (Original work published 2024)