Only a handful of non-invasive and non-painful techniques allow one to record neural activity in humans. Transcranial magnetic stimulation (TMS) is one of them. When applied over primary motor cortex (M1), TMS elicits motor-evoked potentials (MEPs) which provide us with a precise and muscle-specific readout of the excitatory status of the motor output system at the stimulation time. So far, studies have probed motor excitability unilaterally, by eliciting MEPs on one side of the body following single-pulse TMS over contralateral M1. Here, we aimed at evaluating a “Double-Coil” TMS method by which MEPs are elicited in both hands at once.
Grandjean, J., Derosiere, G., Vassiliadis, P., Quemener, L., De Wilde, Y., & Duque, J. (2018). Validation of a new double-coil TMS method to assess corticospinal excitability bilaterally. Front. Neurosci. Conference Proceedings: Belgian Brain Congress 2018, 1(1), 1. https://doi.org/10.3389/conf.fnins.2018.95.00027 (Original work published 2018)