(en) Because of its geographical location, the region Kenscoff-Mahotière (Haiti) is subject to various cases of slope instability due to rough terrain, rainfall, variation of suction in unsaturated soils, earthquakes and clay and limestone formations. These instability problems are mainly the result of modifications in the shear strength of the soils caused by these phenomena. The objective of this thesis is to analyze the influence of these phenomena on slope stability by applying them to slope Kenscoff-Mahotière. In our work, we mainly focus on the progress made in the field of unsaturated soil (suction) and seismicity (earthquake), both in terms of modeling and experimental techniques to study the behaviour of soils under these two factors. Then, we couple them in a parametric approach to the position of the water table and the rainfall in order to take into consideration all the parameters that could cause this instability. To understand these approaches, we performed in situ experimental part a series of geotechnical and geophysical tests, and laboratory on samples taken from the site, tests more specific in saturated and unsaturated conditions to determine the parameters needed to estimate seismic and hydro-mechanical behaviour of soils and evaluate the evolution of their shear strength. Then, in the numerical modeling, we analyzed the stability of Kenscoff-Mahotière. This modeling was performed with the software GEOSLOPE using limit equilibrium methods coupled with finite element methods to analyze the role of these parameters on stability. The applications made from different approaches discussed in our model have also to understand the main causes that may lead to slope rupture Kenscoff-Mahotière.