Intérêt des prébiotiques dans la prise en charge des maladies cardiométaboliques

Delzenne, Nathalie;Neyrinck, Audrey
(2024) Médecine des Maladies Métaboliques — Vol. 18, n° 7, p. 576-579 (2024)

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(en) [Interest of prebiotics in the management of cardiometabolic diseases] Prebiotic dietary fibers are nutrients selectively used by gut microorganisms that confer a health benefit. In the context of obesity and cardiometabolic diseases, placebo-controlled studies reveal individual variability in the favorable metabolic response to prebiotics, which depends, in particular, on the initial composition and evolution of the gut microbiota during the intervention, medication treatments, or the implementation of other concurrent measures (such as physical exercise). Among the mechanisms proposed to explain the metabolic effects of prebiotics, the promotion of endogenous secretion of glucagon-like peptide 1 (GLP-1) appears to be an interesting avenue to explore, given the growing interest in GLP-1 analogs for the treatment of obesity and diabetes.
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Delzenne, N., & Neyrinck, A. (2024). Intérêt des prébiotiques dans la prise en charge des maladies cardiométaboliques. Médecine des Maladies Métaboliques, 18(7), 576-579. https://doi.org/10.1016/j.mmm.2024.09.005 (Original work published 2024)