Arterial grafts: in depth characterization of structure and mechanical properties
(2019) BSTE 2019 — Location: Hasselt (14.November.2019)
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- Authors
Leyssens, Lisa 
- Abstract
- In case of Peripheral Arterial Disease, one of the options is to perform arterial bypass surgery. Bypasses are made using autologous vessels or prosthetic vascular conduits. The limited availability of healthy autologous blood vessels has led to the use of synthetic polymeric material. The mechanical properties of the prosthetic grafts are however quite different from the autologous grafts. While the mechanical strength often provides an appropriate behavior, the existing compliance and biocompatibility mismatch can still cause several complications. In this study, three types of synthetic grafts, Dacron, Gore-Tex and Vectra, were characterized, as well as native tissue. For the 3D structural characterization, high-resolution microCT was used. Strain-controlled planar biaxial tensile testing was used for the mechanical characterization. In this way, we were able to define a cluster of experiments with which the structural and mechanical properties of different graft materials in comparison with the native artery can be defined. The characterization methods that were developed in this work can also be applied to tissue engineered vascular grafts.
- Affiliations
Citations
Leyssens, L., & Bejar Ayllon, N. (2019). Arterial grafts: in depth characterization of structure and mechanical properties. BSTE 2019, Hasselt. https://hdl.handle.net/2078.5/236549