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AbstractEASL-liverfibrosispostSVR-Final.docx
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- Abstract
- Hepatitis C (HCV) recurrence after liver transplantation (LT) is universal if HCV-RNA persists at time of LT and progression to fibrosis can occur rapidly. Nowadays, sustained virological response (SVR) is obtained in 97% of HCV-infected patients treated with direct acting antivirals (DAA) after LT. Fibrosis diminishes in HCV patients after SVR but there is paucity of data on fibrosis regression occurring after SVR following LT. In addition, most studies evaluate fibrosis with non-invasive techniques while these are not validated after LT because of LT-specific complications. There are no data evaluating long-term evolution of fibrosis after SVR since the introduction of DAA treatments (> 5 - 10 years). The aim of this study is to histologically evaluate liver fibrosis evolution in short and long term follow-up biopsies after HCV-elimination in LT-patients.
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Citations
Dahlqvist, G. (2024). Liver fibrosis post SVR. EASL Congress 2024, Milan (Italy). https://hdl.handle.net/2078.5/220287