PET/CT with 18F-FDG- and 18F-FBEM-labeled leukocytes for metabolic activity and leukocyte recruitment monitoring in a mouse model of pulmonary fibrosis.
Idiopathic pulmonary fibrosis is characterized by a progressive and irreversible respiratory failure. Validated noninvasive methods able to assess disease activity are essential for prognostic purposes as well as for the evaluation of emerging antifibrotic treatments.
Bondue, B., Sherer, F., Van Simaeys, G., Doumont, G., Egrise, D., Yakoub, Y., Huaux, F., Parmentier, M., Rorive, S., Sauvage, S., Lacroix, S., Vosters, O., De Vuyst, P., & Goldman, S. (2015). PET/CT with 18F-FDG- and 18F-FBEM-labeled leukocytes for metabolic activity and leukocyte recruitment monitoring in a mouse model of pulmonary fibrosis. The Journal of Nuclear Medicine, 56(1), 127-132. https://doi.org/10.2967/jnumed.114.147421 (Original work published 2014)