[Fulminant thrombotic thrombocytopenic purpura in the course of ciprofloxacin therapy].
(2008) Revue Neurologique — Vol. 158, n° 11, p. 1115-1157 (2002)
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- Authors
- Abstract
- We report on a 43-year-old woman who developed a fulminant thrombotic thrombocytopenic purpura (TTP) in the early course of an oral ciprofloxacin therapy. An acute bacterial meningo-encephalitis with disseminated intravascular coagulation was first suspected. She also presented with haemolytic anaemia and a severe thrombocytopenia. The lumbar puncture was delayed and only performed after platelets transfusions. CSF examination ruled out meningo-encephalitis. A diagnosis of TTP was made and she was given plasma exchanges. However, her neurological status worsened and the cranial CT revealed a subarachnoidal hemorrhage in left sylvian valley with diffuse oedema predominating in the left cerebral hemisphere and multiple ischemic lacunes. She died four days after admission.
- Affiliations
Cliniques St. Elisabeth Service de neurologie
Citations
Mouraux, A., Gille, M., Piéret, F., & Declercq, I. (2008). [Fulminant thrombotic thrombocytopenic purpura in the course of ciprofloxacin therapy]. Revue Neurologique, 158(11), 1115-1157. https://hdl.handle.net/2078.5/51577 (Original work published 2002)