Novel Insights in the Fecal Egg Count Reduction Test for Monitoring Drug Efficacy against Soil-Transmitted Helminths in Large-Scale Treatment Programs.
(2011) PLoS Neglected Tropical Diseases — Vol. 5, n° 12, p. e1427 (2011)
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- Abstract
- The fecal egg count reduction test (FECRT) is recommended to monitor drug efficacy against soil-transmitted helminths (STHs) in public health. However, the impact of factors inherent to study design (sample size and detection limit of the fecal egg count (FEC) method) and host-parasite interactions (mean baseline FEC and aggregation of FEC across host population) on the reliability of FECRT is poorly understood.
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Levecke, B., Speybroeck, N., Dobson, R. J., Vercruysse, J., & Charlier, J. (2011). Novel Insights in the Fecal Egg Count Reduction Test for Monitoring Drug Efficacy against Soil-Transmitted Helminths in Large-Scale Treatment Programs. PLoS Neglected Tropical Diseases, 5(12), e1427. https://doi.org/10.1371/journal.pntd.0001427 (Original work published 2011)