Interoception, the processing of internal bodily states, is essential for constantly informing our brain about our physiological needs and maintaining homeostasis. Interoception contributes to our attitudes, decisions, health behaviors, and emotions. Many empirical studies have thus tested whether interoceptive deficits are associated with risk factors and indicators of mental (e.g., depression) and physical health (e.g., obesity). We argue, however, that the domain of interoception is characterized by significant conceptual and measurement limitations. The objective of this thesis was to explain and provide evidence for these limitations. At the conceptual level, we argued that the definition of interoception and the conceptualization of its dimensions are discrepant with empirical evidence and existing measures. At the measurement level, we showed the low concurrent and discriminant validity of the most frequently used measure of interoceptive accuracy (the Heartbeat Counting Task) even when more optimal instructions are used.