Design and characterization of SERS substrates based on porous silicon membranes infiltrated with gold nanoparticles
(2026)
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- Abstract
- Antimicrobial resistance is driving an urgent need for rapid and reliable diagnostic technologies, but developing biosensors that combine high sensitivity with a clear understanding of their sensing mechanisms remains a significant challenge. This thesis designs and characterizes innovative Surface-Enhanced Raman Scattering (SERS) biosensing substrates based on porous silicon membranes infiltrated with gold nanoparticles, with a particular focus on understanding how the morphology of the porous structure influences signal enhancement. The results demonstrate the potential of these plasmonic materials to generate strong Raman signal amplification while providing valuable insights into the links between porous architecture and SERS performance. By establishing design principles for porous silicon-based SERS platforms, this work lays the groundwork for more sensitive and reliable optical biosensors that could support faster pathogen detection and help combat the spread of antimicrobial resistance.
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Citations
Gevers, C. (2026). Design and characterization of SERS substrates based on porous silicon membranes infiltrated with gold nanoparticles. https://hdl.handle.net/2078.5/281032