PPARα-mediated lipid metabolism reprogramming supports anti-EGFR therapy resistance in head and neck squamous cell carcinoma

Van den bossche, V., Vignau, J., Vigneron, E., Rizzi, I., Zaryouh, H., Wouters, A., Ambroise, J., Van Laere, S., Beyaert, S., Helaers, R., van Marcke, C., Mignion, L., Lepicard, E. Y., Jordan, B. F., Guilbaud, C., Lowyck, O., Dahou, H., Mendola, A., Desgres, M., et al. (2025). PPARα-mediated lipid metabolism reprogramming supports anti-EGFR therapy resistance in head and neck squamous cell carcinoma. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-56675-3 (Original work published 2025)