[Preliminary results] Early prognostic factors in complex regional pain syndrome: a 1-year Belgian prospective longitudinal observational study (NCT05337501)
(2023) 2nd BPS Young Researchers Day 2023 — Location: Gand (22.April.2023)
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- Authors
Halicka, Monika 
- Abstract
- Background and Aims: Complex regional pain syndrome (CRPS) is a still poorly understood condition. Some risk factors have been associated with its incidence but little is known about its (early) prognostic factors and how they influence the long-term outcomes. The aim of this study is to examine the role of biopsychosocial factors in the development of persistent CRPS. Methods: Early CRPS patients (< 6 months from the onset of the condition) are included in a prospective longitudinal observational study and assessed at 4 time points during 1 year (as soon as possible, 4.5, 6 and 12months). Each session includes anamnesis, clinical examination, quantitative sensory testing, visuospatial attentional abilities and questionnaires covering the entire biopsychosocial model. The primary endpoint is the disability. Results: recruitment is ongoing (53 patients included); the following results are the inclusion characteristics of the cohort. The cohort is predominantly female (72.9%) with a mean age of 54 years. 67% worked before the condition onset, only ¼ of them have returned to work. The mean CRPS duration is 83 days while mean CRPS severity score is 12. Function and quality of life are impaired. Mean pain severity is rated at 4.7/10, pain interference is 5.4/10. Participants present pain-related fear. On average, they do not report anxiety or depressive disorders (mean HADS<11). Visuospatial biases are observed mostly in patients with lower limb. Implications: The results of this study will investigate which of these biopsychosocial factors predict long-term outcomes in CRPS. Ultimately, it will allow patients to be stratified according to their risk of chronification.
- Affiliations
Citations
Louis, M.-H., Legrain, V., Filbrich, L., Halicka, M., & Berquin, A. (2023). [Preliminary results] Early prognostic factors in complex regional pain syndrome: a 1-year Belgian prospective longitudinal observational study (NCT05337501). 2nd BPS Young Researchers Day 2023, Gand. https://hdl.handle.net/2078.5/267076