High Inhibition for a Co(II) Tetrazole Bi-pyrazole Dinuclear Complex against Fusarium Oxysporum f. sp. Albedinis
(2024) European Journal of Inorganic Chemistry — Vol. 27, n° 11, p. e202300634 (2024)
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Radi, Smaail 
- Abstract
- New coordination compounds made of two novel tetrazole and C,N-bipyrazole ligands, 2-(3,5,5′-trimethyl-1′H-[1,3′-bipyrazol]-1′-yl)acetonitrile (L1), and 1′-((1H-tetrazol-5-yl)methyl)-3,5,5′-trimethyl-1′H-1,3′-bipyrazole (HL2), were prepared and fully characterized by spectroscopic techniques. Their crystal structures were identified by single-crystal X-ray diffraction revealing mononuclear complexes: [Ni(L1)3](ClO4)2 (1), [Cd(L1)2Cl2] (2), [Cu(HL2)(L2)]ClO4 (3), [Cu(L2)2] (4) and a dinuclear complex [Co2(HL2)(L2)Cl3] (5) comprising CoII ions in octahedral and tetrahedral surrounding within the same unit. Noticeably, 3 and 4 show different architectural structures due to ligand deprotonation as well as the effect of the counter anion. All compounds demonstrated antimicrobial activity against Gram (+) bacteria Listeria innocua and Staphylococcus aureus, as well as Gram (−) bacteria such as Escherichia coli and Pseudomonas aeruginosa, and antifungal activity against pathogenic fungi Geotrichum candidum, Aspergillus niger, and Penicillium crustosum. Interestingly, a high inhibition activity of 97 % was reached for 5 with a low concentration of only 81.1 μmol/L against Fusarium oxysporum f. sp. Albedinis, which is commonly damaging palm trees crops.
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Bahjou, Y., Radi, S., El Massaoudi, M., Draoui, Y., Adarsh, N. N., Miras, H. N., Ferbinteanu, M., Robeyns, K., Ouahhoud, S., Benabbes, R., Hultzsch, K. C., Wolff, M., & Garcia, Y. (2024). High Inhibition for a Co(II) Tetrazole Bi-pyrazole Dinuclear Complex against Fusarium Oxysporum f. sp. Albedinis. European Journal of Inorganic Chemistry, 27(11), e202300634. https://doi.org/10.1002/ejic.202300634 (Original work published 2024)