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Antibiotic Usage in Patients Having Undergone Caesarean Section: A Three-Level Study in Benin

Dohou, Angele;Buda, Valentina;Yemoa, Achille;Anagonu, Séverin;Dalleur, Olivia;et.al.
(2022) Antibiotics — Vol. 11, n° 5, p. 617 [1-12] (2022)

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Abstract
The intense use and misuse of antibiotics is undoubtedly the main factor associated with the high numbers of antibiotic-resistant pathogenic and commensal bacteria worldwide. In low-income countries, this misuse and overuse is widespread, with great consequences at the personal and global levels. In the context of user fee exemptions in caesarean sections, we performed a descriptive study in women to assess the use of antibiotics on three levels—antenatal, during caesarean section, and postpartum—in four Beninese hospitals. Out of the 141 women included, 56.7% were using antibiotics. More than the half (71.3%) were taking more than one antibiotic, either for a long time or in acute treatment. In prophylaxis, the timing, dose, and duration of administration were not correctly achieved. Only 31.2% of women received optimal antibiotic prophylaxis. Various antibiotics including broad-spectrum molecules were used in the patients after caesarean section. The use of antibiotics was improper on the three levels studied. The high rate of self-administered antibiotics, the poor achievement of antibiotic prophylaxis, and the postpartum overuse of antibiotics showed a poor quality of care provided in pregnancy. A national policy is essential to improve the use of antibiotics by the general public as well as by professionals.
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Dohou, A., Buda, V., Yemoa, A., Anagonu, S., Van Bambeke, F., Van Hees, T., Dossou, F., & Dalleur, O. (2022). Antibiotic Usage in Patients Having Undergone Caesarean Section: A Three-Level Study in Benin. Antibiotics, 11(5), 617 [1-12]. https://doi.org/10.3390/ antibiotics11050617 (Original work published 2022)