Substitute fluorescent labeled DNA probe optical imaging, by electrical measurements : impedance spectroscopy, AC current or capacitance, DC current or resistance, photocurrent, etc. Lower cost, high throughput. Si-CMOS mainstream technology for IC integration. Fast point-of-care diagnosis applications. Future lab-on-a-chip miniaturization.
Flandre, D., Moreno Hagelsieb, L., Pampin, R., Laurent, G., Raskin, J.-P., Foultier, B., & Remacle, J. (2005). DNA analytical CMOS-compatible capacitive systems. Proceedings of the Fifth Belgian Day On Biomedical Engineering, 19-23. https://hdl.handle.net/2078.5/254638