Temporal organization of stride duration variability as a marker of gait instability in Parkinson's disease
(2016) Journal of Rehabilitation Medicine — Vol. 48, n° 10, p. 865-871 (2016)
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- Abstract
- Objective: Gait instability and fall risk are major concerns in Parkinson’s disease. This study shows that the temporal or- ganization of gait variability can represent a marker of gait instability that complements standard assessment of motor de cits in Parkinson’s disease. Methods: Temporal organization (long-range autocorrelation; LRA) of stride duration variability, collected from 20 persons with Parkinson’s disease walking overground at a comfort- able speed, was studied. The presence of LRA was based on the scaling properties of the series variability and the shape of the power spectral density. Simultaneously, measures of neu- rological impairment (MDS-UPDRS), balance (BESTest), and balance con dence (ABC-Scale) were collected. To precisely identify the relationship between LRA and functional meas- ures, correlation coef cients were applied. Results: Degradation of LRA was strongly correlated with other clinical scores, in such a way that the temporal organi- zation of gait variability was more random for patients pre- senting with greater motor impairments. Importantly, these measures were relatively independent of age, and gait speed, thus they can be applied to a wide clinical population. Conclusion: The ndings of this study emphasize that tem- poral organization of gait variability is related to degree of functional impairment in Parkinson’s disease. LRA may thus be regarded as an objective and quantitative measure of gait stability for both clinical practice and research.
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Warlop, T., Detrembleur, C., Bollens, B., Stoquart, G., Crevecoeur, F., Jeanjean, A., & Lejeune, T. (2016). Temporal organization of stride duration variability as a marker of gait instability in Parkinson’s disease. Journal of Rehabilitation Medicine, 48(10), 865-871. https://doi.org/10.2340/16501977-2158 (Original work published 2016)