Detection Limit of ultra-scaled Nanowire Biosensors

Afzalian, Aryan;Couniot, Numa;Flandre, Denis
(2012) 2012 SISPAD Conference — Location: Denver (USA) (5.September.2012)

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Authors
  • Afzalian, AryanUCLouvain
    Author
  • Couniot, NumaUCLouvain
    Author
  • Flandre, DenisUCLouvain
    Author
Abstract
The fundamental detection limit of ultra-scaled Si nanowire FET (NWT) biosensors is studied with a NEGF quantum microscopic approach. For negatively charged analytes, a N-doped NWT is found to be more sensitive and to get less sensitivity degradation when increasing channel length. Our results predict threshold voltage shifts due to a single charge analyte on the order of tens to hundreds of mV in dry (air) or low ionic solution environments, which hint at single charge/analyte detection. However, the sensitivity to a single charge analyte rapidly drops down to the mV range in typical ionic solution and SAM conditions.
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Afzalian, A., Couniot, N., & Flandre, D. (2012). Detection Limit of ultra-scaled Nanowire Biosensors. Proceedings of the 2012 SISPAD Conference, 165-168. https://hdl.handle.net/2078.5/252782