Signal-to-noise ratio optimization for detecting bacteria with interdigitated microelectrodes

Couniot, Numa;Flandre, Denis;Francis, Laurent;Afzalian, Aryan
(2013) Sensors and Actuators B: Chemical : international journal devoted to research and development of physical and chemical transducers — p. 9 pages (2013)

Files

NumaCouniot13_01_03_Sensors_Actuators_B-1.pdf
  • Restricted Access
  • Adobe PDF
  • 1.05 MB
Request a copy

Details

Authors
Abstract
Impedimetric sensors can be used for the detection of biological targets, such as bacteria. In this paper, 3D finite-element simulations show that random distributions of bacteria on interdigitated microelectrode sensor surfaces restrict their limit of detection (LOD). We demonstrate the strong influence of the bacteria diameter, surface coverage and electrode geometry on both the sensitivity and the signal-to-noise ratio (SNR). Particularly, we optimize the microelectrode design to maximize the SNR and hence the LOD, and establish that the optimal electrode gap is approximately four times the bacteria diameter. Furthermore, we show that the electrode width and thickness should respectively be minimized and maximized in the considered range with regards to current technological limitations. The paper finally highlights and discusses, from the designer point of view, the critical design tradeoff between SNR and sensitivity maximization.
Affiliations

Citations

  • APA
  • Chicago
  • FWB

Couniot, N., Flandre, D., Francis, L., & Afzalian, A. (2013). Signal-to-noise ratio optimization for detecting bacteria with interdigitated microelectrodes. Sensors and Actuators B: Chemical : international journal devoted to research and development of physical and chemical transducers, 9 pages. https://doi.org/10.1016/j.snb.2012.12.008 (Original work published 2013)