Unraveling age-related impairment of the neuromuscular system: exploring biomechanical and neurophysiological perspectives
(2023) Frontiers in Physiology — Vol. 14, n° 1194889 [1-9], p. 5 (2023)
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- Abstract
- With extended life expectancy, the quality of life of elders is a priority. Loss of mobility, increased morbidity and risks of falls have dramatic individual and societal impacts. Here we consider the age-related modifications of gait, from a biomechanical and neurophysiological perspective. Among the many factors of frailty involved (e.g., metabolic, hormonal, immunological), loss of muscle strength and neurodegenerative changes inducing slower muscle contraction may play a key role. We highlight that the impact of the multifactorial age-related changes in the neuromuscular systems results in common features of gait in the immature gait of infants and older adults. Besides, we also consider the reversibility of age-related neuromuscular deterioration by, on the one hand, exercise training, and the other hand, novel techniques such as direct spinal stimulation (tsDCS).
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Nùñez-Lisboa, M., Valero-Breton, M., & Dewolf, A. (2023). Unraveling age-related impairment of the neuromuscular system: exploring biomechanical and neurophysiological perspectives. Frontiers in Physiology, 14(1194889 [1-9]), 5. https://doi.org/10.3389/fphys.2023.1194889 (Original work published 2023)