Copper-Catalyzed Radical Cascade Annulation for the Preparation of Difluorinated Pyrrolidines and Piperidines
(2023) Synthesis : journal of synthetic organic chemistry — Vol. 55, n° 12, p. 1886-1892 (2022)
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- Abstract
- In this work, we developed a one-pot, copper-catalyzed aminodifluoroalkylation of enylaniline derivatives. This approach allows the catalytic construction of a broad range of pyrrolidines and piperidines substituted with a gem-difluoro moiety.
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Citations
Riant, O., Marchese, M. M., Strähler, S., & Ghiba, L. (2023). Copper-Catalyzed Radical Cascade Annulation for the Preparation of Difluorinated Pyrrolidines and Piperidines. Synthesis : journal of synthetic organic chemistry, 55(12), 1886-1892. https://doi.org/10.1055/a-2004-6031 (Original work published 2022)