Mycophenolic acid quantification in human peripheral blood mononuclear cells using liquid chromatography-tandem mass spectrometry.

Nguyen, Thi Minh;Capron, Arnaud;Mourad, Michel;Wallemacq, Pierre
(2013) Clinical Biochemistry — Vol. 46, n° 18, p. 1909-1911 (2013)

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Authors
  • Nguyen, Thi MinhUCLouvain
    Author
  • Capron, ArnaudUCLouvain
    Author
  • Mourad, MichelUCLouvain
    Author
  • Wallemacq, PierreUCLouvain
    Author
Abstract
We described a robust, rapid and simple method suitable for the determination of MPA concentrations in PBMCs. This method is currently used in pharmacokinetics-pharmacodynamics (PK-PD) clinical trials, in comparison to standard plasma TDM.
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Nguyen, T. M., Capron, A., Mourad, M., & Wallemacq, P. (2013). Mycophenolic acid quantification in human peripheral blood mononuclear cells using liquid chromatography-tandem mass spectrometry. Clinical Biochemistry, 46(18), 1909-1911. https://doi.org/10.1016/j.clinbiochem.2013.09.009 (Original work published 2013)