The fracture toughness of submicron Zr65Ni35 sputter-deposited films is thickness dependent. The failure mechanism involves corrugations for the thickest films and a transition—at 500 nm thickness—to a perfectly flat fracture surface. Bothmechanisms are brittle-type, even though the elastic and plastic properties are independent of thickness and similar to the expected ductile bulk response.Finite-element simulations unravel the origin of the size effect and the transition of failuremode fromthe constraint on plastic dissipation.