Comparative study of collagenase injections versus fasciectomy in Dupuytren's contracture: a 1-year follow-up

Hupez, Alexandre;Detrembleur, Christine;Van Innis, Fernand;Troussel, Serge;Lequint, Thierry;et.al.
(2017) Louvain médical — Vol. 136, n° 4, p. 231-237 (2017)

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Authors
  • Hupez, AlexandreUCLouvain
    Author
  • Detrembleur, Christineorcid-logoUCLouvain
    Author
  • Van Innis, FernandUCLouvain
    Author
  • Troussel, SergeUCLouvain
    Author
  • Libouton, XavierUCLouvain
    Author
  • Lequint, ThierryUCLouvain
    Author
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Abstract
This study sought to evaluate the use of collagenase injections for Dupuytren's contracture (19 compared to fasciectomy, with 19 patients assessed in each group. We measured loss of metacarpophalangeal (MCP) and proximal interphalangeal (PIP) joint extension at baseline and 12 months post-injection, along with its impact on patients' daily life, pain, and satisfaction. Whereas there was no significant between-group difference observed for loss of MCP joint extension, PIP joint extension proved lower for the surgical group compared to the injection group. The injection group exhibited significant improvements in terms of pain, daily activities, and satisfaction regarding the MCP joints, with no between-group differences observed for the PIP joints.
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Hupez, A., Detrembleur, C., Van Innis, F., Troussel, S., Libouton, X., & Lequint, T. (2017). Comparative study of collagenase injections versus fasciectomy in Dupuytren’s contracture: a 1-year follow-up. Louvain médical, 136(4), 231-237. https://hdl.handle.net/2078.5/180011 (Original work published 2017)