Numerous epidemiological studies have demonstrated adverse health effects of a sedentary life style, on the one hand, and of acute and chronic exposure to traffic-related air pollution, on the other. Because physical exercise augments the amount of inhaled pollutants, it is not clear whether cycling to work in a polluted urban environment should be encouraged or not. To address this conundrum we investigated if a bicycle journey along a busy commuting road would induce changes in biomarkers of pulmonary and systematic inflammation in a group of healthy subjects.
Jacobs, L., Nawrot, T. S., de Geus, S., Meeusen, R., Degraeuwe, B., Bernard, A., Sughis, M., Nemery, B., & Panis, L. I. (2010). Subclinical responses in healthy cyclists briefly exposed to traffic-related air pollution: an intervention study. Environmental Health, 9(1). https://doi.org/10.1186/1476-069x-9-64 (Original work published 2010)