EEG and laser stimulation as tools for pain research

Plaghki, Léon;Mouraux, André
(2005) Current Opinion in Investigational Drugs — Vol. 6, n° 1, p. 58-64 (2005)

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Abstract
Laser heat stimulators selectively activate Adelta and C-nociceptors in the superficial layers of the skin. Their high power output produces steep heating ramps, which improve synchronization of afferent volleys and therefore allow the recording of time-locked events, such as laser-evoked brain potentials. Study of the electrical brain activity evoked by Adelta- and C-nociceptor afferent volleys revealed the existence of an extensive, sequentially activated, cortical network. These electrophysiological responses are modulated by stimulus-driven and, even more extensively, top-down processes. The specificity and validity of these components for pain research are currently under intense scrutiny.
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Plaghki, L., & Mouraux, A. (2005). EEG and laser stimulation as tools for pain research. Current Opinion in Investigational Drugs, 6(1), 58-64. https://hdl.handle.net/2078.5/132456 (Original work published 2005)