A Practical Synthesis of 1,2-Nitroamines by Michael Addition of N-Nucleophiles to Nitroalkenes
(2010) Synthesis : journal of synthetic organic chemistry — n° 18, p. 3138-3142 (2010)
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- Authors
- Abstract
- A practical method for the synthesis of alpha-nitroamines by Michael addition of azide to nitroalkene has been developed. This reaction proceeds in high yields under very mild conditions (phase-transfer catalysis) and is found to be general; good yields are obtained with both aryl and alkyl derivatives as well as with 1,1-disubstituted ones.
- Affiliations
Inst Rech Servier Suresnes, France
Citations
Robiette, R., Tran, T.-V., Cordi, A., Tinant, B., & Marchand-Brynaert, J. (2010). A Practical Synthesis of 1,2-Nitroamines by Michael Addition of N-Nucleophiles to Nitroalkenes. Synthesis : journal of synthetic organic chemistry, 18, 3138-3142. https://doi.org/10.1055/s-0030-1258176 (Original work published 2010)