First evidence of high knockdown resistance frequency in Anopheles arabiensis (Diptera: Culicidae) from Ethiopia
(2010) American Journal of Tropical Medicine and Hygiene — Vol. 83, n° 1, p. 122-125 (2010)
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- The status of knockdown resistance (kdr) mutation was investigated in the major malaria vector Anopheles arabiensis Patton (Diptera: Culicidae) from Ethiopia. Among 240 mosquito samples from 15 villages of southwestern Ethiopia that were screened by allele-specific polymerase chain reaction for kdr mutations, the West African kdr mutation (L1014F) was detected in almost all specimens (98.5%), whereas the East African kdr mutation (L1014S) was absent. Moreover, the mortality of An. gambiae s.l. to diagnostic dosages of 4% DDT, 0.75% permethrin, and 0.05% deltamethrin from bioassay results was 1.0%, 18.1%, and 82.2%, respectively. We report here the highest kdr allele frequency ever observed in An. arabiensis and its implications in malaria vector control in Ethiopia are discussed.
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Yewhalaw, D., Van Bortel, W., Denis, L., Coosemans, M., Duchateau, L., & Speybroeck, N. (2010). First evidence of high knockdown resistance frequency in Anopheles arabiensis (Diptera: Culicidae) from Ethiopia. American Journal of Tropical Medicine and Hygiene, 83(1), 122-125. https://doi.org/10.4269/ajtmh.2010.09-0738 (Original work published 2010)