Protein-based polyelectrolyte multilayers

vander Straeten, Aurélien;Lefèvre, Damien;Demoustier, Sophie;Dupont, Christine
(2020) Advances in Colloid and Interface Science — Vol. 280, p. 102161 (2020)

Files

AdvancesinColloidalandInterfaceScience2020.pdf
  • Open Access
  • Adobe PDF
  • 3.08 MB
Download

Details

Authors
Abstract
The immobilization of proteins to impart specific functions to surfaces is topical for chemical engineering, healthcare and diagnosis. Layer-by-Layer (LbL) self-assembly is one of themost usedmethod to immobilizemacromolecules on surfaces. It consists in the alternate adsorption of oppositely charged species, resulting in the formation of a multilayer. This method in principle allows any charged object to be immobilized on any surface, from aqueous solutions. However, when it comes to proteins, the promises of versatility, simplicity and universality that the LbL approach holds are unmet due to the heterogeneity of protein properties. In this review, the literature is analyzed to make a generic approach emerge, with a view to facilitate the LbL assembly of proteins with polyelectrolytes (PEs). In particular, this review aims at guiding the choice of the PE and the building conditions that lead to the successful growth of protein-based multilayered self-assemblies.
Affiliations

Citations

  • APA
  • Chicago
  • FWB

vander Straeten, A., Lefèvre, D., Demoustier, S., & Dupont, C. (2020). Protein-based polyelectrolyte multilayers. Advances in Colloid and Interface Science, 280, 102161. https://doi.org/10.1016/j.cis.2020.102161 (Original work published 2020)