(en) In light of the rapidly changing landscape of haemophilia treatment, the authors of the position paper on the “European Principles of Inhibitor Management” published in 2018 (Table 1) [1] now provide an update on the major impact of novel therapies that bypass and/or substitute clotting factor VIII (FVIII) and IX (FIX) in the care of haemophilia patients with FVIII- or FIX-neutralizing allo-inhibitory antibodies (inhibitors). [...]
Hermans, C., Giangrande, P. L. F., O’Mahony, B., de Kleijn, P., Bedford, M., Batorova, A., Blatný, J., & Jansone, K. (2020). European principles of inhibitor management in patients with haemophilia: implications of new treatment options. Orphanet Journal of Rare Diseases, 15(1), 219 [1-4]. https://doi.org/10.1186/s13023-020-01511-8 (Original work published 2020)