Phosphatidylinositol-3-phosphate(PI3P) is essential for endocytosis and autophagy. VPS38 (endocytosis)and ATG14 (autophagy) are required for localized biosynthesis of PI3P. Liu et al. have shown that mutantarabidopsis (Arabidopsis thaliana)lacking both proteins are viable and synthesize PI3P, suggesting that the enzymatic complex VPS34 can function in absence of these regulatory subunits.
Bhati, K. K., Luong, A.-M., & Batoko, H. (2021). VPS34 Complexes in Plants: Untangled Enough? Trends in Plant Science, 26(4), 303-305. https://doi.org/10.1016/j.tplants.2021.02.001 (Original work published 2021)