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Editorial: The Brain – Gut – Microbiome Network in Metabolic Regulation and Dysregulation

De Meyts, Pierre;Delzenne, Nathalie
(2021) Frontiers in Endocrinology — Vol. 12, p. 760558 [1-2] (2021)

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Abstract
The very nature of endocrinology has undergone major paradigm shifts over the last few decades with the discovery of endocrine functions by organs not hitherto considered as endocrine organs, such as the adipose tissue, the gut and the brain. Those organs release hormones and bioactive compounds acting as metabolism regulators and involved in organ crosstalk. In addition, a major conceptual revolution has taken place in the last few years with the explosion of interest in the role of the symbiosis between eukaryotic cells and the microbes hosted by the animal and human body (microbiome), primarily in the gut [(1); Gérard and Vidal]. The gut microbiome is now recognized as a real functional organ which influences host physiology and plays important roles in digestion, nutrition, immune regulation and metabolism. The organ crosstalk between the brain and the gut including its microbiome was the theme of the 43rd Symposium on Hormones and Cell Regulation held in Mont Ste Odile in Alsace, France, October 10-13, 2018, organized by Nathalie Delzenne and Pierre De Meyts, entitled “The Brain - Gut - Microbiome Network in Metabolic Regulation and Dysregulation”, sponsored by the European Society of Endocrinology. This Frontiers Research Topic with the same title contains four reviews based on lectures given at the Symposium. [...]
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De Meyts, P., & Delzenne, N. (2021). Editorial: The Brain – Gut – Microbiome Network in Metabolic Regulation and Dysregulation. Frontiers in Endocrinology, 12, 760558 [1-2]. https://doi.org/10.3389/fendo.2021.760558 (Original work published 2021)