In this issue, Sawai and colleagues (2022) draw a map of the emerging field of brain organoid ethics. The constitution of this field is dependent on the concept of a brain organoid that would be considered as deserving ethical consideration. Brain organoid research in itself is a broad field and many different entities could qualify as brain organoids, from the early self-organizing neural cell cultures (Lancaster 2013) to organoids modeling this or that part of the brain, until complex physiological systems such as assembloids (Birey 2017), and we might also discuss problems raised by brain organoids made from human material, human-animal chimeras, and so on. While the target article reviews the different questions that might be raised for different kinds of entities, the diversity of entities that we group conveniently under the label brain organoid should not be underestimated...
Botbol-Baum, M., & Gaillard, M. (2022). Pursuit of Perfection? On Brain Organoids as Models. AJOB Neuroscience, 13(2), 79-80. https://doi.org/10.1080/21507740.2022.2048735 (Original work published 2022)