Bilateral Facial Palsy and Rapid Cognitive Decline Indicating Lymphomatosis cerebri: A Case Report
(2022) Clinical Case Reports International — Vol. 6, p. 1383 [1-4] (2022)
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- (en) BACKGROUND: Lymphomatosis cerebri (LC) is a rare variant of Primary Central Nervous System Lymphoma (PCNSL). This unusual presentation differs from systemic lymphoma or intravascular CNS lymphoma. It is often misdiagnosed, leading to delayed diagnosis and treatment. As the literature contains only case reports and small case series, it has not been adequately characterized. CASE REPORT: We present the history of an 85-year-old man with a recent history of bilateral facial palsy. He was admitted with a rapidly progressive cognitive impairment not consistent with delirium. Diagnosis of LC was based on magnetic resonance imaging and cerebrospinal fluid analysis. Due to the patient’s poor health status, biopsy was not performed. He passed away two weeks later. CONCLUSION: To avoid misdiagnosis and delayed treatment of LC, multiple CSF analysis should be performed.
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Citations
Waltener, M., Hanseeuw, B., Benjamin, L., Hugues, J., & Sibille, F.-X. (2022). Bilateral Facial Palsy and Rapid Cognitive Decline Indicating Lymphomatosis cerebri: A Case Report. Clinical Case Reports International, 6, 1383 [1-4]. https://hdl.handle.net/2078.5/102413 (Original work published 2022)