The asthma-anxiety connection: friends or foes?
(2026) Journal of Asthma — Vol. 9, p. 1-5 (2026)
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- Objective: To analyze the relationship between anxiety and asthma. Methods: We carried an English scientific literature search using electronic search engines (PubMed). We included articles published in peer-review journals from 2020 to December 2024. In order to perform the search for the most suitable and representative articles, keywords were selected (-asthma‖, and -anxiety‖). The evidence level was assessed according to the criteria of the Oxford Center For Evidence-Based Medicine. Results: Across multiple studies, the prevalence of anxiety among patients with asthma ranged from 13.7% to 54.3%, consistently higher than in the general population. Anxiety was associated with poorer asthma control (lower ACQ/ACT scores), reduced quality of life (AQLQ) and, in some cases, impaired lung function and higher inflammatory markers (hs-CRP, NLR). Depression emerged as the strongest risk factor for anxiety (OR 26.00), while well-controlled asthma (ACT ≥ 20) and allergic asthma were associated with approximately 70% lower risk. Being female and asthma onset occurring between ages 40 and 59 were also linked to higher anxiety prevalence. Screening tools such as the mini-AQLQ, HADS, EQ-5D and PHQ-4 demonstrated potential utility in identifying anxiety in asthmatic populations. In specific subgroups, asthma-related anxiety was associated with increased symptom reporting and exacerbations, even without a deterioration in objective measurements for airway obstruction. Conclusions: Anxiety is a common comorbidity among patients with asthma and it is associated with poorer disease control and a reduced quality of life.
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Ferreiro-Posse, A., Mendoza-Zambrano, E., Tiotiu-Cepuc, I., & Gonzalez-Barcala, F.-J. (2026). The asthma-anxiety connection: friends or foes? Journal of Asthma, 9, 1-5. https://doi.org/10.1080/02770903.2026.2654583 (Original work published 2026)