Fast FLAIR sequence for detecting major vascular abnormalities during the hyperacute phase of stroke: a comparison with MR angiography

Cosnard, Guy;Duprez, Thierry;Grandin, Cécile;Smith, A. M.;Peeters, André;et.al.
(1999) Neuroradiology : a journal devoted to neuroimaging and interventional neuroradiology — Vol. 41, n° 5, p. 342-346 (1999)

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Authors
  • Cosnard, GuyUCLouvain
    Author
  • Duprez, Thierryorcid-logoUCLouvain
    Author
  • Grandin, CécileUCLouvain
    Author
  • Smith, A. M.
    Author
  • Peeters, AndréUCLouvain
    Author
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Abstract
In the hyperacute phase of stroke, occluded vessels can be seen as high signal on fast-FLAIR images or as absence of flow-related enhancement in maximum-intensity projection (MIP) MR angiography (MRA). To compare these techniques, we examined 53 patients within 6 h of a stroke, using a standardised MRI protocol including fast-FLAIR and 3D time-of-flight TOF MR to detect vessel occlusion or reduced flow corresponding to the suspected ischaemic territory. Brain infarcts were confirmed on MRI after 1-5 days in 41 cases (77%). The overall accuracy of 3D-TOF MRA was 68% and sensitivity, specificity, positive and negative predictive values were 67%, 71%, 87%, and 43% respectively. Values for the fast-FLAIR sequence were: 65%, 85%, 93% and 44%, with an overall accuracy of 70%. The fast-FLAIR sequence was thus able to show occluded vessels or reduced flow with about the same accuracy as 3D-TOF MRA and enabled better prediction of the ischaemic area.
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Cosnard, G., Duprez, T., Grandin, C., Smith, A. M., Munier, T., & Peeters, A. (1999). Fast FLAIR sequence for detecting major vascular abnormalities during the hyperacute phase of stroke: a comparison with MR angiography. Neuroradiology : a journal devoted to neuroimaging and interventional neuroradiology, 41(5), 342-346. https://doi.org/10.1007/s002340050761 (Original work published 1999)