The so-called : « erythema craquelé » of the lower limbs observed in old people is a complication of skin xerosis. It is frequent, may become eczematous (« eczema craquelé ») and is benign in nature. On the contrary, widespread « erythema craquelé » on other parts of the body may also occur in young adults. It requires the search for a paraneoplasic syndrome or a nutritional deficiency. It has also been described as a skin side effect, following a treatment with pemetrexel.
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Lachapelle, J.-M. (2013). L’érythème (eczéma) craquelé: en Dermatologie Quoi de neuf en 2013? Louvain médical, 132(1), 5-10. https://hdl.handle.net/2078.5/187698 (Original work published 2013)