[Effect of Negative Work On Isometric Force in Rat Edl]

Mathias, J.L.;Plaghki, L.;Maréchal, Georges
(1986)

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Authors
  • Mathias, J.L.
    Author
  • Plaghki, L.UCLouvain
    Author
  • Maréchal, GeorgesUCLouvain
    Author
Abstract
(en) Two-month-old Wistar rats are Thalamonal anesthetized. Extensor digitorum longus, (E.D.L) muscle right is isolated respecting its vasculo-nervous pedicle and proximal tendinous insertion. Each muscle receives ten supramaximal tetanic stimulations of 0.4 s at 250 Hz with a rest of 2 min between each contraction. Eighteen rats are divided into three groups of six. In the first group (ISO), the contraction is isometric at the length lo. In the second group (W+), the contraction is isometric for 100 ms at the length lo + 3.6% lo, then the muscle is shortened 7.2% lo at a speed of 12 mm / s or about 40% lo / s. In the third group (W-), the contraction is also isometric for 100 ms but at length lo - 3.6% lo. After which the muscle is stretched at same amplitude and speed as in the previous group. The isometric Fm tetanic force, 100 ms after the start of each stimulation did not decrease in the ISO and W+ groups, In the group W-, Fm decreased very significantly after each contraction. At the 10th contraction, the muscle lost on average 35% ± 6 of its isometric force.
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Citations

Mathias, J. L., Plaghki, L., & Maréchal, G. (1986). [Effect of Negative Work On Isometric Force in Rat Edl]. Archives Internationales de Physiologie et de Biochimie, 94(5), P51-P51. (Original work published 1986)