Highly sensitive detection of beta-2 transferrin in rhinorrhea and otorrhea as a marker for cerebrospinal fluid (C.S.F.) leakage
(1991) Acta Neurochirurgica : the European journal of neurosurgery — Vol. 109, n° 3-4, p. 98-101 (1991)
Files
pdfdocument.pdf
Restricted Access - Adobe PDF
- 495.72 KB
Details
- Authors
- Abstract
- As beta-2 transferrin is almost specific to the cerebrospinal fluid, its detection in rhinorrhea or otorrhea fluids demonstrates the occurrence of CSF fistula. We describe a highly sensitive method based on immunoaffinity-mediated capillary blotting for the detection of this cathodic isoform of transferrin in minute amounts (3-mu-l) of rhinorrhea or otorrhea fluids. Application of this method in a series of 10 patients with CSF fistula is reported.
- Affiliations
Citations
Fransen, P., Sindic, C., Thauvoy, C., Laterre, C., & Stroobandt, G. (1991). Highly sensitive detection of beta-2 transferrin in rhinorrhea and otorrhea as a marker for cerebrospinal fluid (C.S.F.) leakage. Acta Neurochirurgica : the European journal of neurosurgery, 109(3-4), 98-101. https://doi.org/10.1007/BF01403002 (Original work published 1991)