Essential laboratory tests in emergencies; on behalf of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Committee on Preparation of Laboratories for Emergencies (C-PLE)

Lippi, Giuseppe;Alkhazashvili, Maia;Banuls Laetitia, Moreno;Cadamuro, Janne;Plebani, Mario;et.al.
(2026) Clinical Chemistry and Laboratory Medicine (CCLM) — (2026)

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Authors
  • Lippi, Giuseppeorcid-logoSection of Clinical Biochemistry, University of Verona , Verona , Italy
    Author
  • Alkhazashvili, MaiaLugar Center for Public Health Research, National Center for Disease Control and Public Health , Tbilisi , GA
    Author
  • Banuls Laetitia, MorenoDepartment of Laboratory Medicine , Immunohematology and Bloodbank, CHU UCL Namur , Yvoir , Belgium
    Author
  • Cadamuro, JanneDepartment of Laboratory Medicine , Paracelsus Medical University , Salzburg , Austria
    Author
  • Plebani, MarioDepartment of Medicine-DIMED , University of Padova , Padova , Italy
    Author
  • et. al.
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Abstract
This article aims to define a minimum panel of essential laboratory tests to be used in emergency and disaster settings through expert consensus. A structured survey was distributed to the 24 members of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Committee on Preparation of Laboratories for Emergencies (C-PLE). Participants were asked to rate a pre-defined list of diagnostic tests using a four-level priority scale (essential, critical, supportive, not recommended), with scores ranging from 1 to 4. Responses were collected over a two-week period, and mean scores with standard deviations were calculated to classify each test into priority categories. Additional test suggestions were also solicited and evaluated. A total of 20/24 members (83.3 %) completed the survey. Tests classified as essential (mean score 1.00-1.49) included complete blood count, electrolytes (sodium, potassium, chloride), blood glucose, lactate, blood gases (including ionized calcium), urinalysis, and ABO/RhD blood typing. Critical tests (mean score 1.50-2.49) comprised urea and/or creatinine, coagulation parameters such as prothrombin time/international normalized ratio (PT/INR) and activated partial thromboplastin time (APTT), aminotransferases (especially alanine aminotransferase; ALT), and cardiac troponins. Supportive tests (mean score 2.50-3.49) included C-reactive protein, D-dimer, rapid diagnostic tests for
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Lippi, G., Alkhazashvili, M., Banuls Laetitia, M., Cadamuro, J., Danese, E., De Guadiana Romualdo, L., Delacour, H., Favaloro, E., Favresse, J., Henry, B., Jovičić, S., Kütt, M., Ozben, T., Peoc’h, K., Peretz, A., Perović, A., Quaresima, V., Thachil, J., Yucel, D., et al. (2026). Essential laboratory tests in emergencies; on behalf of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Committee on Preparation of Laboratories for Emergencies (C-PLE). Clinical Chemistry and Laboratory Medicine (CCLM). Accepted/in-press. https://doi.org/10.1515/cclm-2026-0577 (Original work published 2026)