Allergen-antibody complexes in the treatment of atopic dermatitis: preliminary results of a double-blind placebo-controlled study.

Leroy, Bernard P.;Boden, G.;Jacquemin, Marie-Antoinette;Lachapelle, Jean-Marie;Saint-Remy, J M
(1992) Acta Dermato-Venereologica. Supplementum — Vol. 176, p. 129-131 (1992)

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Authors
  • Leroy, Bernard P.UCLouvain
    Author
  • Boden, G.
    Author
  • Jacquemin, Marie-AntoinetteUCLouvain
    Author
  • Lachapelle, Jean-MarieUCLouvain
    Author
  • Saint-Remy, J M
    Author
Abstract
Twenty-three adult patients suffering from chronic atopic dermatitis (AD) have been treated by regular injections of complexes made of D. pteronyssinus allergens and specific autologous antibodies. A double-blind placebo-controlled protocol was followed for 4 months, then the patients were treated openly to complete a full year on active therapy. Preliminary results are presented for the first 8 months. Seventy-three percent of patients improved when treated with complexes, showing a mean improvement of more than 70% after 4 months. This study suggests that injections of allergen-antibody complexes is an effective treatment of at least some forms of AD and confirms that airborne allergens are significant exacerbating factors of AD.
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Leroy, B. P., Boden, G., Jacquemin, M.-A., Lachapelle, J.-M., & Saint-Remy, J. M. (1992). Allergen-antibody complexes in the treatment of atopic dermatitis: preliminary results of a double-blind placebo-controlled study. Acta Dermato-Venereologica. Supplementum, 176, 129-131. https://hdl.handle.net/2078.5/50072 (Original work published 1992)