Carbapenem-resistant Acinetobacter baumannii isolates were obtained from 17 patients between September 2004 and August 2005 at the Academisch Ziekenhuis Vrije Universiteit Brussel, Brussels, Belgium. These multidrug-resistant isolates, which belonged to a single clone, remained susceptible to colistin and tigecycline only and produced the carbapenem-hydrolyzing oxacillinase OXA-58. This study highlights the importance of the intercountry spread of this beta-lactamase-mediated resistance mechanism and its epidemic evolution.
Bogaerts, P., Naas, T., Wybo, I., Bauraing, C., Soetens, O., Piérard, D., Nordmann, P., & Glupczynski, G. (2006). Outbreak of infection by carbapenem-resistant Acinetobacter baumannii producing the carbapenemase OXA-58 in Belgium. Journal of Clinical Microbiology, 44(11), 4189-4192. https://doi.org/10.1128/JCM.00796-06 (Original work published 2006)