Trials and tribulations of in vitro fertilization after ovarian tissue transplantation.
(2019) Fertility and sterility — Vol. 112, n° 5, p. 817-818 (2019)
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- (en) In their systematic review of ovarian stimulation and assisted reproductive technology (ART) outcomes in women who have undergone ovarian tissue transplantation (OTT) (1), Andersen et al. attempt to provide a consistent overview of the current state of play, which is no easy task given the heterogeneous and often discrepant data available on the subject. Indeed, questions raised in this article concerning issues of oocyte quality, poor ovarian reserve, empty follicle syndrome, and unfavorable in vitro fertilization (IVF) outcomes have not significantly changed since we first sought to address them more than 10 years ago, when we evaluated the quality of oocytes and embryos derived from frozen-thawed transplanted ovarian tissue in a series of women who had not conceived after 12 months of spontaneous cycles after OTT (2). In that study, the empty follicle rate per oocyte retrieval was 29% and the percentage of abnormal oocytes (immature or degenerated) was 38%. [...]
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Citations
Dolmans, M.-M. (2019). Trials and tribulations of in vitro fertilization after ovarian tissue transplantation. Fertility and sterility, 112(5), 817-818. https://doi.org/10.1016/j.fertnstert.2019.07.1347 (Original work published 2019)