The fetal gallbladder is visualized from 14 weeks of gestation as an anechoic structure located below the liver in the right anterosuperior quadrant of the abdomen. Non‐visualization of the gallbladder occurs in only 0.1% of pregnancies1 and has been reported in association with a range of abnormalities, from benign gallbladder agenesis or empty gallbladder, to aneuploidies, cystic fibrosis (CF) and biliary atresia (BA), all of which carry a poor prognosis (Table 1)1-5. Based on two cases, we examined the potential utility of fetal blood sampling when the gallbladder could not be visualized by prenatal imaging. [...]
Muller, F., Bernard, P., Salomon, L. J., Dreux, S., Allaf, B., Czerkiewicz, I., & Ville, Y. (2015). Role of fetal blood sampling in cases of non-visualization of fetal gallbladder. Ultrasound in Obstetrics and Gynecology, 46(6), 743-744. https://doi.org/10.1002/uog.14888 (Original work published 2015)