Automated immunoassay for reliable measurement of sex hormone binding globulin (SHBG).

Gruson, D;Maisin, D;Fillee, C
(2011) Clinical Laboratory : journal for clinical laboratories and laboratories related to blood transfusion —

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  • Gruson, D
    Author
  • Maisin, D
    Author
  • Fillee, C
    Author
Abstract
BACKGROUND: Sex hormone binding globulin (SHBG) is important for the transport and regulation of distribution of sex steroids. METHODS: The performance of the Architect SHBG automated immunoassay in comparison to radioimmunoassay was evaluated using 62 patient specimens. Furthermore, specimen from 100 healthy individuals were used to establish a preliminary reference interval for this automated assay. RESULTS: The assay has demonstrated overall good analytical performance and was significantly correlated with the reference method. CONCLUSIONS: The Architect SHBG assay is a good method for routine measurement of SHBG circulating levels.

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Gruson, D., Maisin, D., & Fillee, C. (2011). Automated immunoassay for reliable measurement of sex hormone binding globulin (SHBG). Clinical Laboratory : journal for clinical laboratories and laboratories related to blood transfusion. https://hdl.handle.net/2078.5/90027