Interferon β-1b-neutralizing antibodies 5 years after clinically isolated syndrome.
(2011) Neurology — Vol. 77, n° 9, p. 835-843 (2011)
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- Abstract
- Although NAb positivity was associated with increased brain MRI activity, no discernible effects on clinical outcomes were found. This finding may reflect the greater power of MRI compared with clinical outcomes to detect the treatment effects of IFNβ-1b and may also result from temporal changes in NAb titers and biology.
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Hartung, H.-P., Freedman, M. S., Polman, C. H., Edan, G., Kappos, L., Miller, D. H., Montalbán, X., Barkhof, F., Petkau, J., White, R., Sahajpal, V., Knappertz, V., Beckmann, K., Lanius, V., Sandbrink, R., Pohl, C., & Sindic, C. (2011). Interferon β-1b-neutralizing antibodies 5 years after clinically isolated syndrome. Neurology, 77(9), 835-843. https://doi.org/10.1212/WNL.0b013e31822c90d7 (Original work published 2011)