Impact of Oxygenation Status on (18)F-FDG Uptake in Solid Tumors

Neveu, Marie-Aline; Bol, Vanesa; Bol, Anne; Grégoire, Vincent; Gallez, Bernard

doi:10.1007/978-1-4939-3023-4_25

Impact of Oxygenation Status on (18)F-FDG Uptake in Solid Tumors

Neveu, Marie-Aline

;

Bol, Vanesa

;

Bol, Anne

;

Grégoire, Vincent

;

Gallez, Bernard

(2016) Advances in Experimental Medicine and Biology — Vol. 876, p. 201-207 (2016)

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Authors

Neveu, Marie-AlineUCLouvain
Author
Bol, VanesaUCLouvain
Author
Bol, AnneUCLouvain
Author
Grégoire, VincentUCLouvain
Author
Gallez, BernardUCLouvain
Author

Abstract

The influence of changes in tumor oxygenation (monitored by EPR oximetry) on the uptake of (18)F-FDG tracer was evaluated using micro-PET in two different human tumor models. The (18)F-FDG uptake was higher in hypoxic tumors compared to tumors that present a pO2 value larger than 10 mmHg.

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Neveu, M.-A., Bol, V., Bol, A., Grégoire, V., & Gallez, B. (2016). Impact of Oxygenation Status on (18)F-FDG Uptake in Solid Tumors. Advances in Experimental Medicine and Biology, 876, 201-207. https://doi.org/10.1007/978-1-4939-3023-4_25 (Original work published 2016)