Sulfenome mining in Arabidopsis thaliana
(2014) Proceedings of the National academy of sciences of the United States of America — Vol. 111, n° 31, p. 11545-11550 (2014)
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- Abstract
- stress. The in vivo YAP1-based trapping of sulfenylated proteins was validated by a targeted in vitro analysis of DEHYDROASCORBATE REDUCTASE2 (DHAR2). In DHAR2, the active site nucleophilic cysteine is regulated through a sulfenic acid-dependent switch, leading to S-glutathionylation, a protein modification that protects the protein against oxidative damage.
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Waszczak, C., Van Breusegem, F., Messens, J., Van Montagu, M., De Jaeger, G., Gevaert, K., Vertommen, D., De Smet, B., Van Molle, I., Bodra, N., Wahni, K., Persiau, G., Eeckhout, D., & Akter, S. (2014). Sulfenome mining in Arabidopsis thaliana. Proceedings of the National academy of sciences of the United States of America, 111(31), 11545-11550. https://doi.org/10.1073/pnas.1411607111 (Original work published 2014)