Vessel based delineation guidelines for the elective lymph node regions in breast cancer radiation therapy - PROCAB guidelines

Verhoeven, Karolien;Weltens, Caroline;Remouchamps, Vincent;Hortobagyi, Eszter;Kirkove, Carine;et.al.
(2015) Radiotherapy & Oncology — Vol. 114, n° 1, p. 11-16 (2015)

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Authors
  • Verhoeven, KarolienUniversity Hospitals Leuven/KU Leuven, Belgium
    Author
  • Weltens, CarolineUniversity Hospitals Leuven/KU Leuven, Belgium
    Author
  • Remouchamps, VincentClinique Sainte Elisabeth (AMPR), Namur, Belgium
    Author
  • Hortobagyi, EszterUniversity Hospitals Leuven/KU Leuven, Belgium
    Author
  • Author
  • Kirkove, CarineUCLouvain
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Abstract
Objective A national project to improve the quality of breast radiation therapy was started, named PROCAB (PROject on CAncer of the Breast). One of the objectives was to reach a national consensus guideline for the delineation of the regional lymph node areas in breast radiation therapy. Methods The realization of the new guidelines was a step by step process that started with multiple expert meetings where the existing guidelines were analyzed and the delineations of the lymph node regions were performed together with a surgeon, specialized in the anatomy of the drainage of the breast. Results The delineation guidelines are vessel-based. Since the occurrence of pathological lymph nodes is typically around the veins, the cranial and caudal borders of all different nodal regions are based on a 5 mm margin around the veins, except for the parasternal lymph node area. Compared to the existing guidelines there are some major changes. Conclusion With this project a national as well as a European (ESTRO) consensus guideline for the delineation of the regional lymph node areas in breast RT is reached. The new delineation atlas is vessel-based and no longer field-based.
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Citations

Verhoeven, K., Weltens, C., Remouchamps, V., Hortobagyi, E., Veldeman, L., Lengelé, B., Mahjoubi, K., & Kirkove, C. (2015). Vessel based delineation guidelines for the elective lymph node regions in breast cancer radiation therapy - PROCAB guidelines. Radiotherapy & Oncology, 114(1), 11-16. https://doi.org/10.1016/j.radonc.2014.11.008 (Original work published 2015)